WebFeb 28, 2024 · One of the main problems in chemotherapy using platinum drugs as anticancer agents is the resistance phenomenon. Synthesizing and evaluating valid alternative compounds is challenging. This review focuses on the last two years of progress in the studies of platinum (II)- and platinum (IV)-based anticancer complexes. In … WebFeb 11, 2024 · Cisplatin is used to treat a wide range of childhood cancers and cisplatin-induced hearing loss (CIHL) is a common and debilitating …
Chemotherapy and hearing loss: Monitoring is essential
WebPatients were randomized 1:1 to receive cisplatin-based chemotherapy without (cisplatin alone arm) or with sodium thiosulfate (e.g., Pedmark) (Pedmark + cisplatin arm). The major efficacy outcome measure was hearing loss assessed by American Speech-Language-Hearing Association (ASHA) criteria; hearing was assessed at baseline and 4 weeks … WebFeb 26, 2024 · The cisplatin ototoxicity occurs between 23% and 50% in adults and up to 60% in children [4,6]. However, some studies have reported elevated hearing thresholds in up to 100% of cisplatin-treated cancer patients [7,8], while it is estimated to be 63% with aminoglycosides and 6-7% with furosemide [9]. how to retrieve pokemon from gym
Drug Prevents Chemo-Related Hearing Loss in Some …
WebJun 1, 2024 · Hearing loss likely occurs in all cancers that are treated with cisplatin. Cisplatin is the most ototoxic drug in clinical use. It also happens to be a fantastic cancer drug. It is used to treat a wide variety of solid tumors in … WebCisplatin is one of the most effective chemotherapy agents, used in just under half of pediatric cancer cases. Permanent hearing loss is a common side effect of this … WebNov 21, 2024 · Cisplatin chemotherapy causes permanent hearing loss in 40–80% of treated patients. It is unclear whether the cochlea has unique sensitivity to cisplatin or is exposed to higher levels of the... how to retrieve photos from broken samsung