WebIn the most accepted theoretical model for somite segmentation, the clock and wavefront (CW) model, a clock that ticks to determine particular timings and a wavefront that … The clock and wavefront model is a model used to describe the process of somitogenesis in vertebrates. Somitogenesis is the process by which somites, blocks of mesoderm that give rise to a variety of connective tissues, are formed. The model describes the splitting off of somites from the paraxial mesoderm … See more Once the cells of the pre-somitic mesoderm are in place following by cell migration during gastrulation, oscillatory expression of many genes begins in these cells as if regulated by a developmental "clock." This has … See more • Segmentation • Gastrulation • Signal transduction See more Gene oscillation in presomitic cells is largely, but not completely, cell autonomous. When Notch signaling is disrupted in zebrafish, neighboring cells no longer oscillate synchronously, indicating that Notch signaling is important for keeping … See more • Cooke, J.; Zeeman, Christopher (1976). "A clock and wavefront model for control of the number of repeated structures during animal … See more
HYBRID REACTION-DIFFUSION AND CLOCK-AND …
WebSep 4, 2024 · Abstract. The clock and wavefront paradigm is arguably the most widely accepted model for explaining the embryonic process of somitogenesis. According to this … WebAug 21, 2011 · Here we present an alternative formulation of the clock and wavefront model in which oscillator coupling, already known to play a key role in oscillator … human daily cycle
[2009.02364] Hybrid reaction-diffusion and clock-and …
WebAnatomical terminology. [ edit on Wikidata] Somitogenesis is the process by which somites form. Somites are bilaterally paired blocks of paraxial mesoderm that form along the anterior-posterior axis of the developing embryo in segmented animals. In vertebrates, somites give rise to skeletal muscle, cartilage, tendons, endothelium, and dermis . WebJul 28, 2015 · This process is thought to be regulated by a mechanism known as the “clock and wavefront model”, first proposed by J Cooke and EC Zeeman in 1976. The model describes an interaction between a wavefront which moves through the PSM and a ticking clock in each cell which determines its ability to respond to the signal given by the … Webclock and the wavefront are the leading factors during the entire process in which TBX6 gene plays an important role. TBX6 is a member of the T-box gene family, and its important pathogenicity in spinal deformity has been confirmed. Several TBX6 gene variants and novel pathogenic mechanisms have been recently revealed, and human data interaction networkplus