WebAntimicrobial peptides (AMPs) can be used as alternative therapeutic agents to traditional antibiotics. These peptides have abundant natural template sources and can be isolated from animals, plants, and microorganisms. They are amphiphilic and mostly net positively charged, and they have a broad-spectrum inhibitory effect on bacteria, fungi, and … WebApr 11, 2024 · However, this α-helix anticancer peptide risks haemolysis when used at high doses, which limits its further application. This study aims to prepare a pH-responsive liposome, Der-loaded-pHSL, using nanotechnology to avoid the haemolysis risk of Dermaseptin-PP and increase its accumulation in tumour sites to enhance efficacy and …
Bacterial anti-microbial peptides and nano-sized drug delivery systems ...
WebJan 25, 2024 · The concepts of polymer−peptide conjugation and self-assembly were applied to antimicrobial peptides (AMPs) in the development of a targeted antimalaria … WebJan 25, 2024 · Antimicrobial peptides (AMPs) have a great potential to face the global expansion of antimicrobial resistance (AMR) associated to the development of … blasorchester perlach
Drug Delivery Systems for the Oral Administration of Antimicrobial ...
WebJan 2, 2024 · The introduction of antibiotics has revolutionized the treatment and prevention of microbial infections. However, the global spread of pathogens resistant to available antibiotics is a major concern. Recently, the WHO has updated the priority list of multidrug-resistant (MDR) species for which the discovery of new therapeutics is urgently needed. … WebJan 3, 2024 · Developments of antimicrobial peptides and potential delivery systems are promising for therapeutic applications in the future. References Abdel-Sayed P, Kaeppeli … WebAug 1, 2024 · Significance statement. Antimicrobial peptides hold promise to supplement small molecules antibiotics and combat the multidrug resistant microbes. There are however technical hurdles towards the clinical applications, largely due to the limitation of the stability and bioavailability of peptides. Here we review recent studies in delivery and ... frankay sister act 2