Phenytoin interactions bnf

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August undefined, 2024

WebRivaroxaban causes bleeding, as can Flurbiprofen ; concurrent use might increase the risk of developing this effect. Manufacturer advises use with caution or avoid. Severity: Severe. Evidence: Theoretical. WebPhenytoin is used to prevent and control seizures (also called an anticonvulsant or antiepileptic drug). It works by reducing the spread of seizure activity in the brain. How to use phenytoin...

Phenytoin Interactions BNF NICE

WebSome side-effects (such as headache, ataxia, drowsiness, nausea, vomiting, blurring of vision, dizziness and allergic skin reactions) are dose-related, and may be dose-limiting. These side-effects are more common at the start of treatment. WebDrug interaction information Severe interactions are highlighted with a red marker. Find out more about BNF interactions information Belumosudil 20 interactions Antacids Antacids is predicted to decrease the exposure to Belumosudil. Manufacturer advises separate administration by 12 hours. Severity: Moderate Evidence: Theoretical Apalutamide geochemistry programs colorado

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WebPhenytoin may cause swelling and bleeding of the gums. Massage your gums and brush and floss your teeth regularly to minimize this problem. See your dentist regularly. WebFind out more about BNF interactions information. List of interactions for Maribavir. 27 interactions . Apalutamide. ... Phenytoin. Phenytoin is predicted to decrease the exposure to Maribavir. Manufacturer advises avoid or adjust Maribavir dose. Severity: Severe. Evidence: Study. Primidone. geochemistry short course

Sedating antihistamines Prescribing information - CKS NICE

Maribavir Interactions BNF NICE

WebIn patients with myoclonic seizures, the use of carbamazepine, gabapentin, oxcarbazepine, phenytoin, pregabalin, tiagabine, or vigabatrin is not recommended because they may exacerbate seizures. A Strength of recommendation: High Lamotrigine may also occasionally exacerbate myoclonic seizures. Web20 interactions Antacids Antacids is predicted to decrease the exposure to Belumosudil. Manufacturer advises separate administration by 12 hours. Severity: Moderate Evidence: Theoretical Apalutamide Apalutamide is predicted to decrease the exposure to Belumosudil. Manufacturer advises adjust Belumosudil dose. Severity: Severe Evidence: Study chris johnson return to runningWebPhenytoin is classified as an antiarrhythmic and can cause SA and AV nodal blocks as well as dysrhythmias due to its effect on voltage-gated sodium channels. 3 Further, since phenytoin is poorly soluble, the parenteral form is administered with propylene glycol, which is a cardiac depressant. 3 The infusion rate of parenteral phenytoin should ... geochemistry services

"WebPhenytoin is predicted to decrease the exposure to Maribavir. Manufacturer advises avoid or adjust Maribavir dose. Severity: Severe Evidence: Study Primidone Primidone is predicted to decrease the exposure to Maribavir. Manufacturer advises avoid or adjust Maribavir dose. Severity: Severe Evidence: Study Rifabutin " - Phenytoin interactions bnf

Phenytoin interactions bnf

Phenytoin: Uses, Interactions, Mechanism of Action

WebCommon or very common. Asthenia; chills; dizziness; drowsiness; dry mouth; dysarthria; euphoric mood; headache; hypotension; movement disorders; nausea; nystagmus; sensation abnormal; skin reactions; stupor; taste altered; tinnitus; tremor; vasodilation; vertigo; vision disorders; vomiting. WebDrug interactions which occur with folic acid include: Carbamazepine — levels may be reduced if taken concurrently with folic acid. Monitor carbamazepine concentrations and adjust the dose accordingly. Fluorouracil — levels may be increased producing toxicity. Avoid concurrent use with folic acid.

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WebAdverse effects. Blood disorders — leukopenia, megaloblastic anaemia, thrombocytopenia, agranulocytosis, methaemoglobinaemia. Gastrointestina l — nausea, diarrhoea, vomiting (common). Nervous system — aseptic meningitis (frequency unknown). Skin — pruritus, and skin rashes (common). WebFind out more about BNF interactions information Apixaban 127 interactions Acalabrutinib Apixaban causes bleeding, as can Acalabrutinib ; concurrent use might increase the risk of developing this effect. Manufacturer advises use with caution or avoid. Severity: Severe Evidence: Theoretical Aceclofenac

WebThe majority of these interactions arise because phenytoin is a potent inducer of cytochrome P450 microsomal enzymes, and therefore may increase the clearance of drugs which are extensively metabolised; drugs affected include carbamazepine, theophylline, methadone, prednisolone, dexamethasone, metyrapone and several cardiac … Web2. máj 2024 · An overdose of phenytoin can be fatal. Overdose symptoms may include twitching eye movements, slurred speech, loss of balance, tremor, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. What to avoid Avoid drinking alcohol while you are taking phenytoin.

WebFind out more about BNF interactions information. List of interactions for . 27 interactions . Apalutamide. ... Phenytoin is predicted to decrease the exposure to Maribavir. Manufacturer advises avoid or adjust Maribavir dose. Severity: Severe. Evidence: Study. Primidone. WebFosphenytoin. Valproate affects the concentration of Fosphenytoin and Fosphenytoin decreases the concentration of Valproate. Manufacturer advises monitor concentration. Severity: Severe.

WebSince systemic absorption can follow topical application of ciprofloxacin, the possibility of interactions should be borne in mind. Ciprofloxacin has the following interaction information: Drug interaction information

Web9 interactions Capecitabine Folic acid is predicted to increase the risk of toxicity when given with Capecitabine. Manufacturer makes no recommendation. Severity: Severe Evidence: Anecdotal Fluorouracil Folic acid is predicted to increase the risk of toxicity when given with Fluorouracil. Manufacturer advises avoid. Severity: Severe Evidence: geochemistry pythonWebBNF Interactions A to Z Interactions A to Z Browse drugs by A to Z to check for interactions. Includes information on the severity of an interaction and the type of evidence to support it. A B C D E F G H I K L M N O P Q R S T U V W X Y Z A Abacavir Abatacept Abemaciclib Abiraterone Abrocitinib Acalabrutinib Acarbose Acebutolol Aceclofenac geochemistry suWebPhenytoin — chlorphenamine inhibits phenytoin metabolism and can lead to phenytoin toxicity. If symptoms of toxicity are present (confusion, blurred vision, nystagmus, ataxia, or drowsiness), monitor serum phenytoin levels and reduce the dose if necessary. Drug interactions associated with all antihistamines include: chris johnson scruffs